Human Immunodeficiency Virus (HIV)-1 Integration Sites in Viral Latency
نویسندگان
چکیده
منابع مشابه
Human Immunodeficiency Virus (HIV)-1 Integration Sites in Viral Latency
The persistence of human immunodeficiency virus type 1 (HIV-1) in latent reservoirs is a major barrier to HIV cure. Reservoir establishment depends on low viral expression that may be related to provirus integration sites (IS). In vitro, in cell lines and primary T cells, latency is associated with specific IS through reduced viral expression mediated by transcriptional interference by host cel...
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ژورنال
عنوان ژورنال: Current HIV/AIDS Reports
سال: 2015
ISSN: 1548-3568,1548-3576
DOI: 10.1007/s11904-014-0241-9